Sutaria N, Alphonse MP, Marani M, Parthasarathy V, Deng J, Wongvibulsin S, Williams K, Roh YS, Choi J, Bordeaux Z, Pritchard T, Dillen C, Semenov YR, Kwatra MM, Archer NK, Garza LA, Dong X, Kang S, Kwatra SG. Cluster analysis of circulating plasma biomarkers in prurigo nodularis reveals a distinct systemic inflammatory signature in African Americans. J Invest Dermatol. 2021 Oct 22:S0022-202X(21)02383-6. doi: 10.1016/j.jid.2021.10.011. Epub ahead of print. PMID: 34717952

Wongvibulsin S, Sutaria N, Kannan S, Alphonse MP, Belzberg M, Williams KA, Brown ID, Choi J, Roh YS, Pritchard T, Khanna R, Eseonu AC, Jedrych J, Dillen C, Kwatra MM, Chien AL, Archer N, Garza LA, Dong X, Kang S, Kwatra SG. Transcriptomic analysis of atopic dermatitis in African Americans is characterized by Th2/Th17-centered cutaneous immune activation. Sci Rep. 2021 May 27;11(1):11175. doi: 10.1038/s41598-021-90105-w. PMID: 34045476; PMCID: PMC8160001

Belzberg M, Alphonse MP, Brown I, Williams KA, Khanna R, Ho B, Wongvibulsin S, Pritchard T, Roh YS, Sutaria N, Choi J, Jedrych J, Johnston AD, Sarkar K, Vasavda C, Meixiong J, Dillen C, Bondesgaard K, Paolini JF, Chen W, Corcoran D, Devos N, Kwatra MM, Chien AL, Archer NK, Garza LA, Dong X, Kang S, Kwatra SG. Prurigo Nodularis Is Characterized by Systemic and Cutaneous T Helper 22 Immune Polarization. J Invest Dermatol. 2021 Sep;141(9):2208-2218.e14. doi: 10.1016/j.jid.2021.02.749. Epub 2021 Mar 23. PMID: 33771530; PMCID: PMC8384659.

Patel SP, Khanna R, Choi J, Williams KA, Roh YS, Hong MS, Sutaria NH, Pritchard T, Kwatra MM, Kwatra SG. Sleep disturbance in adults with chronic pruritic dermatoses is associated with increased C-reactive protein levels. J Am Acad Dermatol. 2021 Feb;84(2):265-272. doi: 10.1016/j.jaad.2020.08.059. Epub 2020 Aug 19. PMID: 32822785.

Patel SP, Khanna R, Belzberg M, Kang S, Kwatra SG. Elevated Blood Cadmium and Lead Levels in Chronic Pruritic Dermatoses. J Invest Dermatol. 2020 Jan;140(1):238-241. doi: 10.1016/j.jid.2019.06.130. Epub 2019 Jun 26. PMID: 31254516.

Roh YS, Khanna R, Patel SP, Gopinath S, Williams KA, Khanna R, Pritchard T, Sutaria N, Choi J, Alphonse MP, Kwatra MM, Kwatra SG. Circulating blood eosinophils as a biomarker for variable clinical presentation and therapeutic response in patients with chronic pruritus of unknown origin. J Allergy Clin Immunol Pract. 2021 Jun;9(6):2513-2516.e2. doi: 10.1016/j.jaip.2021.01.034. Epub 2021 Feb 3. PMID: 33548514.

 

Clinical Research

Kwatra SG. Breaking the Itch-Scratch Cycle in Prurigo Nodularis. N Engl J Med. 2020 Feb 20;382(8):757-758. doi: 10.1056/NEJMe1916733. PMID: 32074425.

Kwatra SG, Ständer S, Kang H. PD-1 Blockade-Induced Pruritus Treated with a Mu-Opioid Receptor Antagonist. N Engl J Med. 2018 Oct 18;379(16):1578-1579. doi: 10.1056/NEJMc1805637. PMID: 30332571.

Sutaria N, Adawi W, Goldberg R, Roh YS, Choi J, Kwatra SG. Itch: pathogenesis and treatment. J Am Acad Dermatol. 2021 Oct 11:S0190-9622(21)02635-9. doi: 10.1016/j.jaad.2021.07.078. Epub ahead of print. PMID: 34648873

Roh YS, Choi J, Sutaria N, Kwatra SG. Itch: epidemiology, clinical presentation, and diagnostic workup. J Am Acad Dermatol. 2021 Aug 21:S0190-9622(21)02369-0. doi: 10.1016/j.jaad.2021.07.076. Epub ahead of print. PMID: 34428534

Huang AH, Williams KA, Kwatra SG. Prurigo nodularis: Epidemiology and clinical features. J Am Acad Dermatol. 2020 Dec;83(6):1559-1565. doi: 10.1016/j.jaad.2020.04.183. Epub 2020 May 23. PMID: 32454098.

Khanna R, Kwon CD, Patel SP, Belzberg M, Williams KA, Khanna R, Boozalis E, Kwatra SG. Intranasal butorphanol rescue therapy for the treatment of intractable pruritus: A case series from the Johns Hopkins Itch Clinic. J Am Acad Dermatol. 2020 Nov;83(5):1529-1533. doi: 10.1016/j.jaad.2020.07.017. Epub 2020 Jul 15. PMID: 32679280.

Roh YS, Sutaria N, Biles NF, Kwatra SG. Treatment of Chronic Pruritus With Medical Marijuana. JAMA Dermatol. 2021 Jul 1;157(7):879-880. doi: 10.1001/jamadermatol.2021.1194. PMID: 33835147.

 

Racial and Ethnic Disparities Research

Sutaria N, Adawi W, Brown I, Parthasarathy V, Roh YS, Choi J, Bordeaux ZA, Trinh P, Le TK, Deng J, Semenov YR, Kwatra SG. Racial disparities in mortality among patients with prurigo nodularis: A multi-center cohort study. J Am Acad Dermatol. 2021 Sep 21:S0190-9622(21)02510-X. doi: 10.1016/j.jaad.2021.09.028. Epub ahead of print. PMID: 34560195

McColl M, Boozalis E, Aguh C, Eseonu AC, Okoye GA, Kwatra SG. Pruritus in Black Skin: Unique Molecular Characteristics and Clinical Features. J Natl Med Assoc. 2021 Feb;113(1):30-38. doi: 10.1016/j.jnma.2020.07.002. Epub 2020 Aug 1. PMID: 32747312.

Boozalis E, Tang O, Patel S, Semenov YR, Pereira MP, Stander S, Kang S, Kwatra SG. Ethnic differences and comorbidities of 909 prurigo nodularis patients. J Am Acad Dermatol. 2018 Oct;79(4):714-719.e3. doi: 10.1016/j.jaad.2018.04.047. Epub 2018 May 4. PMID: 29733939; PMCID: PMC6518410.

Bell MA, Whang KA, Thomas J, Aguh C, Kwatra SG. Racial and Ethnic Disparities in Access to Emerging and Frontline Therapies in Common Dermatological Conditions: A Cross-Sectional Study. J Natl Med Assoc. 2020 Dec;112(6):650-653. doi: 10.1016/j.jnma.2020.06.009. Epub 2020 Jul 5. PMID: 32641259.

Whang KA, Khanna R, Thomas J, Aguh C, Kwatra SG. Racial and Gender Differences in the Presentation of Pruritus. Medicines (Basel). 2019 Sep 27;6(4):98. doi: 10.3390/medicines6040098. PMID: 31569651; PMCID: PMC6963580.

 

Epidemiological Research

Whang KA, Le TK, Khanna R, Williams KA, Roh YS, Sutaria N, Choi J, Gabriel S, Chavda R, Semenov Y, Kwatra SG. Health-related quality of life and economic burden of prurigo nodularis. J Am Acad Dermatol. 2021 May 28:S0190-9622(21)01028-8. doi: 10.1016/j.jaad.2021.05.036. Epub ahead of print. PMID: 34058278

Roh YS, Huang AH, Sutaria N, Choi U, Wongvibulsin S, Choi J, Bordeaux ZA, Parthasarathy V, Deng J, Patel DP, Canner JK, Grossberg AL, Kwatra SG. Real-world comorbidities of atopic dermatitis in the US adult ambulatory population. J Am Acad Dermatol. 2021 Nov 18:S0190-9622(21)02838-3. doi: 10.1016/j.jaad.2021.11.014. Epub ahead of print. PMID: 34800600.

Roh YS, Huang AH, Sutaria N, Choi U, Wongvibulsin S, Choi J, Bordeaux ZA, Parthasarathy V, Deng J, Patel DP, Canner JK, Grossberg AL, Kwatra SG. Real-world comorbidities of atopic dermatitis in the US adult ambulatory population. J Am Acad Dermatol. 2021 Nov 18:S0190-9622(21)02838-3. doi: 10.1016/j.jaad.2021.11.014. Epub ahead of print. PMID: 34800600.

Whang KA, Mahadevan V, Bakhshi PR, Williams KA, Gabriel S, Chavda R, Kwatra SG. Prevalence of prurigo nodularis in the United States. J Allergy Clin Immunol Pract. 2020 Oct;8(9):3240-3241. doi: 10.1016/j.jaip.2020.05.051. Epub 2020 Jun 9. PMID: 32531481.

Wongvibulsin S, Sutaria N, Williams KA, Huang AH, Choi J, Roh YS, Hong M, Kelley D, Pahalyants V, Murphy W, Alphonse MP, Bakhshi P, Walia A, Semenov YR, Kwatra SG. A Nationwide Study of Prurigo Nodularis: Disease Burden and Healthcare Utilization in the United States. J Invest Dermatol. 2021 Oct;141(10):2530-2533.e1. doi: 10.1016/j.jid.2021.02.756. Epub 2021 Apr 3. PMID: 33823182; PMCID: PMC8603386.

 

Books

Shawn G. Kwatra. Pathogenesis and Treatment of Chronic Pruritus. MDPI AG, 2020. 

Yosipovitch, Gil, and Shawn G. Kwatra. Living with Itch: A Patient’s Guide. JHU Press, 2013.